Endonuclease V, also known as deoxyinosine 3′-endonuclease, is a DNA repair enzyme that specifically recognizes deoxyinosine (dI)—the deamination product of deoxyadenosine—in both double-stranded and single-stranded DNA. It cleaves the second phosphodiester bond 3′ to the deoxyinosine, generating a nick with a 3′-hydroxyl and a 5′-phosphate terminus. To a lesser extent, the enzyme also acts on AP sites, urea residues, base-pair mismatches, insertion/deletion mismatches, hairpin structures, unpaired loop regions.
相关产品
T4 PNK
目录号：
ON-1095
T3 DNA ligase
目录号：
ON-1188
2′, 3′-ddI
目录号：
D6-006
CAS编号：
69655-05-06
分子式：
C10H12N4O3
N4-Bz-3′-NH2-ddC
目录号：
D3-032
分子式：
C16H18N4O4
N6-Bz-3′-NH2-ddA
目录号：
D1-029
分子式：
C17H18N6O3
N6-dmf-3′-NH2-ddA
目录号：
D1-054
分子式：
C13H19N7O2
N2-iBu-3′-NH2-ddG
目录号：
D2-018
分子式：
C14H20N6O4
2-NH2-ddA
目录号：
D1-022
分子式：
C10H14N6O2