Endonuclease V, also known as deoxyinosine 3′-endonuclease, is a DNA repair enzyme that specifically recognizes deoxyinosine (dI)—the deamination product of deoxyadenosine—in both double-stranded and single-stranded DNA. It cleaves the second phosphodiester bond 3′ to the deoxyinosine, generating a nick with a 3′-hydroxyl and a 5′-phosphate terminus. To a lesser extent, the enzyme also acts on AP sites, urea residues, base-pair mismatches, insertion/deletion mismatches, hairpin structures, unpaired loop regions.
関連製品
T4 PNK
カタログ番号：
ON-1095
T3 DNA ligase
カタログ番号：
ON-1188
5-carboxy-UTP, 100 mM Sodium Salt Solution
カタログ番号：
R5-192
分子式：
C10H15N2O17P3 (free acid)
5-CH2OH-CTP, 100 mM Sodium Salt Solution
カタログ番号：
R3-154
分子式：
C10H18N3O15P3 (free acid)
5-hydroxymethyl-dUTP, 100mM Sodium Salt solution
カタログ番号：
D5-080
分子式：
C10H17N2O15P3 (free acid)
5-MOM-Uridine-5′-triphosphate, 100 mM Sodium Salt Solution
カタログ番号：
R5-177
分子式：
C11H19N2O16P3 (free acid)
N1-MOM-Pseudouridine-5′-triphosphate, 100 mM Sodium Salt Solution
カタログ番号：
R5-178
分子式：
C11H19N2O16P3 (free acid)
N1-Me-ATP, 100mM Sodium salt solution
カタログ番号：
R1-182
分子式：
C11H18N5O13P3 (free acid)