Oligonucleotide and mRNA manufacturing infrastructure

Capacity and supply chain security built for global delivery

Hongene Biotech’s RNA-focused state-of-the-art manufacturing sites provide the capacity, resilience, and quality required to support customers worldwide. Our infrastructure is designed to advance oligonucleotide and mRNA programs seamlessly — from early development through to commercial supply.

Manufacturing

  • Shanghai (2012): ISO-certified production of phosphoramidites, GalNAc, NTPs and cap analogs
  • Shanghai (2020): Expanded capacity for ISO-certified raw materials
  • Shanghai (2021): GMP mRNA CDMO services for DS, LNP formulation and fill-finish
  • Shanghai (2024): GMP oligonucleotide CDMO services for DS and DP
  • Hungary (2027): European GMP oligonucleotide CDMO services and ISO-certified raw materials

Global distribution

  • North America (San Francisco): R&D center, warehouse and client support hub
  • EMEA (Hamburg): Regional warehouse ensuring secure European supply

Commercial

  • Boston, Hamburg, Tokyo: Regional offices providing local sales, logistics, and customer service

Sales Office / R&D Center / Warehouse

Address:

29520 Kohoutek Way, Union City, CA 94587

Sales Office

Address:

One Broadway, 14th floor Cambridge, MA 02142

Sales Office / Warehouse

Address:

Grossmoorbogen 25, 21079 Hamburg

Sales Office

Address:

403, Kanda lwamotocho Plaza Building, 2-4-1 Iwamoto-Cho, Chiyoda-Ku, Tokyo

mRNA CDMO Facility

Address:

9F, Building 315-1, No.333 Guiping Road, Shanghai, China

Manufacturing Facility (2020)

Address:

No. 88, Chuhua Branch Road, Fengxian District, Shanghai, China, 201417

Manufacturing Facility (2012)

Address:

No.60, Beishagang Road, Minhang District, Shanghai, China, 201100